Publications

@article{Calandra2024,

title = {From proton transfer to ionic liquids: How isolated domains of ion pairs grow to form extended network in diphenyl phosphate-bis(2-ethylhexyl) amine mixtures},

author = {Pietro Calandra and Paolino Caputo and Cesare Oliviero Rossi and Maciej Kozak and Michał Taube and Mikolaj Pochylski and Jacek Gapinski},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85187796682&doi=10.1016%2fj.molliq.2024.124402&partnerID=40&md5=ed4087e14b792ad95fcc6e6f6e407cc3},

doi = {10.1016/j.molliq.2024.124402},

issn = {01677322},

year  = {2024},

date = {2024-01-01},

journal = {Journal of Molecular Liquids},

volume = {399},

publisher = {Elsevier B.V.},

abstract = {Hypothesis: Diphenyl phosphate (DPP)/bis(2-ethylhexyl) amine (BEEA) liquid mixtures are expected to show peculiar self-assembly behavior due to their, respectively, acidic and basic nature which can trigger acid-base reaction. Experiment: The properties of DPP/BEEA mixtures of different compositions are explored by a combined theoretical (Ab initio calculations) and experimental (rheology, X-ray and light scattering) approach. Findings: (i) a proton transfer from DPP to BEEA takes place with formation of cationic and anionic species in liquid phase (ion pair formation); (ii) due to the strong and long-range electrostatic interactions, each of the two charged species is preferentially surrounded by the other one, in a picture resembling the structure of ionic materials; (iii) this gives rise to a striking viscosity increase takes place as DPP concentration increases; (iv) the composition dependencies of all measured parameters show clear deviations around DPP molar fraction of 0.2, indicating unequivocally the formation of isolated domains, formed by DPP-BEEA pairs which coalescence/percolate into a unique, extended, network at higher DPP concentrations. © 2024 The Authors},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Szlachetko2023,

title = {Correction to: SOLARIS National Synchrotron Radiation Centre in Krakow, Poland (The European Physical Journal Plus, (2023), 138, 1, (10), 10.1140/epjp/s13360-022-03592-9)},

author = {Jakub Szlachetko and Jacek Szade and Edyta Beyer and Wojciech Błachucki and Piotr Ciochoń and Paul Dumas and Kinga Freindl and Grzegorz Gazdowicz and Sebastian Glatt and Krzysztof Guła and Josef Hormes and Paulina Indyka and Agnieszka Klonecka and Jacek Kołodziej and Tomasz Kołodziej and Józef Korecki and Paweł Korecki and Filip Kosiorowski and Karolina Kosowska and Grzegorz Kowalski and Maciej Kozak and Paulina Kozioł and Wojciech M. Kwiatek and Danuta Liberda and Henning Lichtenberg and Ewa Madej and Anna Mandziak and Andrzej Marendziak and Krzysztof Matlak and Alexey Maximenko and Paweł Nita and Natalia Olszowska and Roman Panaś and Ewa Partyka-Jankowska and Marcel Piszak and Alexander Prange and Michał Rawski and Maciej Roman and Marcin Rosmus and Marcin Sikora and Joanna Sławek and Tomasz Sobol and Katarzyna Sowa and Nika Spiridis and Joanna Stępień and Magdalena Szczepanik and Michał Ślęzak and Tomasz Ślęzak and Tolek Tyliszczak and Grzegorz Ważny and Jarosław Wiechecki and Dorota Wilgocka-Ślęzak and Barbara Wolanin and Paweł Wróbel and Tomasz Wróbel and Marcin Zając and Adriana Wawrzyniak and Marek Stankiewicz},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85164193837&doi=10.1140%2fepjp%2fs13360-023-04211-x&partnerID=40&md5=058ea06bdd44c3e59a433cc4a4560931},

doi = {10.1140/epjp/s13360-023-04211-x},

issn = {21905444},

year  = {2023},

date = {2023-01-01},

journal = {European Physical Journal Plus},

volume = {138},

number = {7},

publisher = {Springer Science and Business Media Deutschland GmbH},

abstract = {In this article, author Michał Ślęzak has been added to the author list. The original article has been corrected. © 2023, The Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2023,

title = {Proceedings of the 17th International Conference on X-Ray Absorption Fine Structure (XAFS 2018)},

author = {Maciej Kozak and Wojciech Kwiatek and Maya Kiskinova and Augusto Marcelli and Sakura Pascarelli},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85093951137&doi=10.1016%2fj.radphyschem.2020.109001&partnerID=40&md5=eb63f5cee89b57769a6037131e409557},

doi = {10.1016/j.radphyschem.2020.109001},

issn = {0969806X},

year  = {2023},

date = {2023-01-01},

journal = {Radiation Physics and Chemistry},

volume = {202},

publisher = {Elsevier Ltd},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kurpiewska2023,

title = {The Promise and Challenge of High Pressure Macromolecular Crystallography},

author = {Katarzyna Kurpiewska and Joanna Sławek and Agnieszka Klonecka and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85156145163&doi=10.3390%2fcryst13040560&partnerID=40&md5=65f87b62764b7a8c287ef98d6b97a102},

doi = {10.3390/cryst13040560},

issn = {20734352},

year  = {2023},

date = {2023-01-01},

journal = {Crystals},

volume = {13},

number = {4},

publisher = {MDPI},

abstract = {Since its introduction in the early 1970s, high pressure crystallography (HPX) has shown great potential for the investigation of different types of matter. Using diamond anvil cells, HPX is an emerging technique that has been rapidly implemented, making it available to biologists, and there is immense potential for utilizing this technique in biological systems in the future. At the molecular level, high-pressure crystallographic investigation provides information on structural characteristics that not only determine the native conformation of a protein but also the conformations with higher free-energy, thus revealing function-related structural changes and properties that can be modified as a result of pressurization. The increase in the number of crystal structures of different macromolecules determined under high pressure over the last five decades can be ascribed mainly to two factors: the emergence of high-pressure cells with very large, open angles, and the advent of third generation synchrotron sources. The use of high pressure crystallography as a research tool has been shown to contribute to the advancements in the basic fields of biochemistry (protein misfolding and aggregation), biophysics (protein stability), and biotechnology (food processing). Presently, with a growing interest in biomedicine and nanotechnology, this nonstandard method appears to be a valid instrument for probing more challenging and complex systems. In this review, we present the method, highlight a selection of recent applications, and describe challenges for high pressure macromolecular crystallography (HPMX). © 2023 by the authors.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Szlachetko2023b,

title = {SOLARIS national synchrotron radiation centre in Krakow, Poland},

author = {Jakub Szlachetko and Jacek Szade and Edyta Beyer and Wojciech Błachucki and Piotr Ciochoń and Paul Dumas and Kinga Freindl and Grzegorz Gazdowicz and Sebastian Glatt and Krzysztof Guła and Josef Hormes and Paulina Indyka and Agnieszka Klonecka and Jacek Kołodziej and Tomasz Kołodziej and Józef Korecki and Paweł Korecki and Filip Kosiorowski and Karolina Kosowska and Grzegorz Kowalski and Maciej Kozak and Paulina Kozioł and Wojciech Kwiatek and Danuta Liberda and Henning Lichtenberg and Ewa Madej and Anna Mandziak and Andrzej Marendziak and Krzysztof Matlak and Alexey Maximenko and Paweł Nita and Natalia Olszowska and Roman Panaś and Ewa Partyka-Jankowska and Marcel Piszak and Alexander Prange and Michał Rawski and Maciej Roman and Marcin Rosmus and Marcin Sikora and Joanna Sławek and Tomasz Sobol and Katarzyna Sowa and Nika Spiridis and Joanna Stępień and Magdalena Szczepanik and Tomasz Ślęzak and Tolek Tyliszczak and Grzegorz Ważny and Jarosław Wiechecki and Dorota Wilgocka-Ślęzak and Barbara Wolanin and Paweł Wróbel and Tomasz Wróbel and Marcin Zając and Adriana Wawrzyniak and Marek Stankiewicz},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146024175&doi=10.1140%2fepjp%2fs13360-022-03592-9&partnerID=40&md5=5e0ebd68d305845f0eddf8d8ba575bb0},

doi = {10.1140/epjp/s13360-022-03592-9},

issn = {21905444},

year  = {2023},

date = {2023-01-01},

journal = {European Physical Journal Plus},

volume = {138},

number = {1},

publisher = {Springer Science and Business Media Deutschland GmbH},

abstract = {The SOLARIS synchrotron located in Krakow, Poland, is a third-generation light source operating at medium electron energy. The first synchrotron light was observed in 2015, and the consequent development of infrastructure lead to the first users’ experiments at soft X-ray energies in 2018. Presently, SOLARIS expands its operation towards hard X-rays with continuous developments of the beamlines and concurrent infrastructure. In the following, we will summarize the SOLARIS synchrotron design, and describe the beamlines and research infrastructure together with the main performance parameters, upgrade, and development plans. © 2023, The Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wojcieszak2022,

title = {Surface activity and phytotoxicity of morpholinium herbicidal ionic liquids},

author = {Marta Wojcieszak and Barbara Krupa and Anna Syguda and Filip Walkiewicz and Michalina Wilkowska and Maciej Kozak and Katarzyna Materna},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85133928808&doi=10.1016%2fj.molliq.2022.119750&partnerID=40&md5=d8b595082e8e308e21eb552007a28f44},

doi = {10.1016/j.molliq.2022.119750},

issn = {01677322},

year  = {2022},

date = {2022-01-01},

journal = {Journal of Molecular Liquids},

volume = {362},

publisher = {Elsevier B.V.},

abstract = {The use of efficient synthesis methods to obtain novel herbicidal ionic liquids (HILs) with biological activity is extremely important because it can eliminate certain negative environmental impacts. The authors of this work succeeded in the experiment, which resulted in the synthesis of 18 novel ionic liquids with high yields. Furthermore, a number of physicochemical and biological properties have been investigated, including surface activity, thermal analysis, and phytotoxicity. In addition, it was proven that morpholinium ionic liquids with phenoxyacid anions were more effective against cress than HILs previously studied in the literature. To the best of our knowledge, this is the first report of surface-active ionic liquids with herbicidal anions where leaf surfaces were used for analysis. An important aspect of this work was to compare the wettability of the surfaces of wheat leaves and weeds. Moreover, it was shown that using paraffin as a reference surface was not sufficient to describe the wetting properties of HILs. The research reported here proved that morpholinium ionic liquids were effective in wetting weed surfaces while they do not adversely affect wheat leaf surfaces. Our results could be significant for meeting the environmental challenges and agricultural demands of the future. © 2022 The Authors},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Calandra2021,

title = {Non-ideal mixing behavior in dibutyl phosphate-propylamine binary liquids: Dielectric and nuclear magnetic resonance investigations},

author = {Pietro Calandra and Vincenzo Turco Liveri and Noemi Proietti and Donatella Capitani and Domenico Lombardo and Catalin Gainaru and Roland Böhmer and Maciej Kozak and Maria Dobies and Zbigniew Fojud and Mikolaj Pochylski},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098459151&doi=10.1016%2fj.molliq.2020.114963&partnerID=40&md5=74bb34292716305e3fbe38ad1092d4c5},

doi = {10.1016/j.molliq.2020.114963},

issn = {01677322},

year  = {2021},

date = {2021-01-01},

journal = {Journal of Molecular Liquids},

volume = {323},

publisher = {Elsevier B.V.},

abstract = {Owing to the amphiphilic nature of their constituent molecules, binary mixtures of pure liquid surfactants are usually characterized by enhanced nano-segregation and thus can exhibit interesting transport properties and complex macroscopic behavior. In this ambit it was recently shown by Turco Liveri et al. (J. Mol. Liq. 263 (2018) 274–281) at room temperature that mixtures of short aliphatic chains compounds, such as dibutyl phosphate (DBP) and n-propylamine (PA) liquids, due to their ability to allow for phosphate-to-amine proton transfer, display ionic liquid–like behavior with composition-dependent enhanced conductivity, viscosity, and magnetically-induced birefringence. To understand the molecular mechanisms at the basis of this behavior, in the present study a combination of nuclear magnetic resonance (NMR) and dielectric spectroscopy investigations has been carried out for the same materials for different amine molar ratios. It was found that at certain compositions all studied dynamical processes (conformational changes, local hopping of “free” protons among neighboring polar headgroups, long-range charge migration) exhibit significant deviations from ideal mixing behavior. The microscopic origin of these deviations is discussed. © 2020},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2020,

title = {Proceedings of the 17thInternational Conference on X-Ray Absorption Fine Structure (XAFS 2018)},

author = {Maciej Kozak and Wojciech M. Kwiatek and Maya Kiskinova and Augusto Marcelli and Sakura Pascarelli},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085921077&doi=10.1016%2fj.radphyschem.2020.108985&partnerID=40&md5=23666280f4dacd125cef43a6b3d1468b},

doi = {10.1016/j.radphyschem.2020.108985},

issn = {0969806X},

year  = {2020},

date = {2020-01-01},

journal = {Radiation Physics and Chemistry},

volume = {175},

publisher = {Elsevier Ltd},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Harding2020,

title = {Magnetic Moments of Short-Lived Nuclei with Part-per-Million Accuracy: Toward Novel Applications of ß -Detected NMR in Physics, Chemistry, and Biology},

author = {R. D. Harding and S. Pallada and J. Croese and A. Antušek and M. Baranowski and M. L. Bissell and L. Cerato and K. M. Dziubinska-Kühn and W. Gins and F. P. Gustafsson and A. Javaji and R. B. Jolivet and A. Kanellakopoulos and B. Karg and M. Kempka and V. Kocman and M. Kozak and K. Kulesz and M. Madurga Flores and G. Neyens and R. Pietrzyk and J. Plavec and M. Pomorski and A. Skrzypczak and P. Wagenknecht and F. Wienholtz and J. Wolak and Z. Xu and D. Zakoucky and M. Kowalska},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098574792&doi=10.1103%2fPhysRevX.10.041061&partnerID=40&md5=8ed78ca586a220ff1a6f1672b7d66ec9},

doi = {10.1103/PhysRevX.10.041061},

issn = {21603308},

year  = {2020},

date = {2020-01-01},

journal = {Physical Review X},

volume = {10},

number = {4},

publisher = {American Physical Society},

abstract = {We determine for the first time the magnetic dipole moment of a short-lived nucleus with part-per-million (ppm) accuracy. To achieve this 2-orders-of-magnitude improvement over previous studies, we implement a number of innovations into our ß-detected nuclear magnetic resonance (ß-NMR) setup at ISOLDE at CERN. Using liquid samples as hosts, we obtain narrow, subkilohertz-linewidth, resonances, while a simultaneous in situ H1 NMR measurement allows us to calibrate and stabilize the magnetic field to ppm precision, thus eliminating the need for additional ß-NMR reference measurements. Furthermore, we use ab initio calculations of NMR shielding constants to improve the accuracy of the reference magnetic moment, thus removing a large systematic error. We demonstrate the potential of this combined approach with the 1.1 s half-life radioactive nucleus Na26, which is relevant for biochemical studies. Our technique can be readily extended to other isotopic chains, providing accurate magnetic moments for many short-lived nuclei. Furthermore, we discuss how our approach can open the path toward a wide range of applications of the ultrasensitive ß-NMR in physics, chemistry, and biology. © 2020 authors. Published by the American Physical Society.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Mieloch2018,

title = {The influence of ligand charge and length on the assembly of Brome mosaic virus derived virus-like particles with magnetic core},

author = {Adam A. Mieloch and Monika Krȩcisz and Jakub D. Rybka and Aleksander Strugała and Michał Krupiński and Anna Urbanowicz and Maciej Kozak and Bohdan Skalski and Marek Figlerowicz and Michael Giersig},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85043345223&doi=10.1063%2f1.5011138&partnerID=40&md5=2027a375e857f9280333e17d7988454c},

doi = {10.1063/1.5011138},

issn = {21583226},

year  = {2018},

date = {2018-01-01},

journal = {AIP Advances},

volume = {8},

number = {3},

publisher = {American Institute of Physics Inc.},

abstract = {Virus-like particles (VLPs) have sparked a great interest in the field of nanobiotechnology and nanomedicine. The introduction of superparamagnetic nanoparticles (SPIONs) as a core, provides potential use of VLPs in the hyperthermia therapy, MRI contrast agents and magnetically-powered delivery agents. Magnetite NPs also provide a significant improvement in terms of VLPs stability. Moreover employing viral structural proteins as self-assembling units has opened a new paths for targeted therapy, drug delivery systems, vaccines design, and many more. In many cases, the self-assembly of a virus strongly depends on electrostatic interactions between positively charged groups of the capsid proteins and negatively charged nucleic acid. This phenomenon imposes the negative net charge as a key requirement for the core nanoparticle. In our experiments, Brome mosaic virus (BMV) capsid proteins isolated from infected plants Hordeum vulgare were used. Superparamagnetic iron oxide nanoparticles (Fe3O4) with 15 nm in diameter were synthesized by thermal decomposition and functionalized with COOH-PEG-PL polymer or dihexadecylphosphate (DHP) in order to provide water solubility and negative charge required for the assembly. Nanoparticles were characterized by Transmission Electron Microscopy (TEM), Dynamic Light Scattering (DLS), Zeta Potential, Fourier Transformed Infrared Spectroscopy (FTIR) and Superconducting Quantum Interference Device (SQUID) magnetometry. TEM and DLS study were conducted to verify VLPs creation. This study demonstrates that the increase of negative surface charge is not a sufficient factor determining successful assembly. Additional steric interactions provided by longer ligands are crucial for the assembly of BMV SPION VLPs and may enhance the colloidal stability. © 2018 Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Razew2018,

title = {Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components},

author = {Michal Razew and Zbigniew Warkocki and Michal Taube and Adam Kolondra and Mariusz Czarnocki-Cieciura and Elzbieta Nowak and Karolina Labedzka-Dmoch and Aleksandra Kawinska and Jakub Piatkowski and Pawel Golik and Maciej Kozak and Andrzej Dziembowski and Marcin Nowotny},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042766937&doi=10.1038%2fs41467-017-02570-5&partnerID=40&md5=a7a3f5c2979d03bf50648f0da9f4ed65},

doi = {10.1038/s41467-017-02570-5},

issn = {20411723},

year  = {2018},

date = {2018-01-01},

journal = {Nature Communications},

volume = {9},

number = {1},

publisher = {Nature Publishing Group},

abstract = {Nuclease and helicase activities play pivotal roles in various aspects of RNA processing and degradation. These two activities are often present in multi-subunit complexes from nucleic acid metabolism. In the mitochondrial exoribonuclease complex (mtEXO) both enzymatic activities are tightly coupled making it an excellent minimal system to study helicase-exoribonuclease coordination. mtEXO is composed of Dss1 3′-To-5′ exoribonuclease and Suv3 helicase. It is the master regulator of mitochondrial gene expression in yeast. Here, we present the structure of mtEXO and a description of its mechanism of action. The crystal structure of Dss1 reveals domains that are responsible for interactions with Suv3. Importantly, these interactions are compatible with the conformational changes of Suv3 domains during the helicase cycle. We demonstrate that mtEXO is an intimate complex which forms an RNA-binding channel spanning its entire structure, with Suv3 helicase feeding the 3′ end of the RNA toward the active site of Dss1. © 2017 The Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Paczkowska2018149,

title = {Effects of inclusion of cetirizine hydrochloride in β-cyclodextrin},

author = {Magdalena Paczkowska and Mikołaj Mizera and Kornelia Lewandowska and Maciej Kozak and Andrzej Miklaszewski and Judyta Cielecka-Piontek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85049843039&doi=10.1007%2fs10847-018-0808-y&partnerID=40&md5=ef6cf3f4bd50dcda9e21287488514042},

doi = {10.1007/s10847-018-0808-y},

issn = {09230750},

year  = {2018},

date = {2018-01-01},

journal = {Journal of Inclusion Phenomena and Macrocyclic Chemistry},

volume = {91},

number = {3-4},

pages = {149 – 159},

publisher = {Springer Netherlands},

abstract = {Following the preparation of inclusion complex of cetirizine (CTZ) and β-cyclodextrin (β-CD), the compound was investigated to assess the possibility of modifying the physicochemical properties (solubility, release, stability, permeability) of CTZ after complexation that are vital for subsequent formulation studies involving the said complex. Changes in FT-IR/Raman spectra, DSC thermograms and XRD diffractograms confirmed the formation of a CTZ–β-CD system. Hydrophilic interaction chromatography with a DAD detector was employed to determine alterations of the CTZ concentration during studies following complexation. An analysis of a phase-solubility diagram of cCTZ = fcβ-CD indicated a linear rise in the solubility of CTZ as the concentration of β-CD increased. The inclusion of CTZ in a system with β-CD significantly reduced the instability of CTZ in the presence of oxidizing factors. It was also found that regardless of the pH of the acceptor fluids used in the release studies an increase was observed in the concentration of CTZ in CD system compared to its free form. The ability to permeate artificial biological membranes manifested by CTZ after complexation was enhanced as well. In summary, CD has significant potential to mask the bitter taste of CTZ and to counter the instability induced by oxidizing factors. © 2018, The Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Chrabaszczewska2018,

title = {Cyclic trimer of human cystatin C, an amyloidogenic protein - Molecular dynamics and experimental studies},

author = {Magdalena Chrabaszczewska and Martyna Maszota-Zieleniak and Zuzanna Pietralik and Michał Taube and Sylwia Rodziewicz-Motowidło and Aneta Szymańska and Kosma Szutkowski and Daniel Clemens and Anders Grubb and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046881900&doi=10.1063%2f1.5023807&partnerID=40&md5=682a4f30fb225fc75a05e08293ed59b5},

doi = {10.1063/1.5023807},

issn = {00218979},

year  = {2018},

date = {2018-01-01},

journal = {Journal of Applied Physics},

volume = {123},

number = {17},

publisher = {American Institute of Physics Inc.},

abstract = {Human cystatin C (HCC) is a cysteine protease inhibitor that takes a series of oligomeric forms in solution (e.g., dimers, trimers, tetramers, decamers, dodecamers, and other higher oligomers). The best-known form of cystatin C is the dimer, which arises as a result of a domain swapping mechanism. The formation of the HCC oligomeric forms, which is most likely due to this domain swapping mechanism, is associated with the aggregation of HCC into amyloid fibrils and deposits. To investigate the structure of a specific HCC oligomer, we developed a covalently stabilized trimer of HCC. An atomic model of this HCC trimer was proposed on the basis of molecular docking and molecular dynamics simulations. The most stable model of the HCC trimer obtained from the molecular dynamics simulations is characterized by a well-preserved secondary structure. The molecular size and structural parameters of the HCC trimer in solution were also confirmed by Small Angle Neutron Scattering and Nuclear Magnetic Resonance Diffusometry. © 2018 Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Murawska2017136,

title = {Overall conformation of covalently stabilized domain-swapped dimer of human cystatin C in solution},

author = {Magdalena Murawska and Aneta Szymańska and Anders Grubb and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014678969&doi=10.1016%2fj.nimb.2017.02.090&partnerID=40&md5=e01c1e8fead9ee0d00940475c162b4ce},

doi = {10.1016/j.nimb.2017.02.090},

issn = {0168583X},

year  = {2017},

date = {2017-01-01},

journal = {Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms},

volume = {411},

pages = {136 – 140},

publisher = {Elsevier B.V.},

abstract = {Human cystatin C (HCC), a small protein, plays a crucial role in inhibition of cysteine proteases. The most common structural form of human cystatin C in crystals is a dimer, which has been evidenced both for the native protein and its mutants. In these structures, HCC dimers were formed through the mechanism of domain swapping. The structure of the monomeric form of human cystatin C was determined for V57N mutant and the mutant with the engineered disulfide bond (L47C)–(G69C) (known as stab1-HCC). On the basis of stab1-HCC, a number of covalently stabilized oligomers, including also dimers have been obtained. The aim of this study was to analyze the structure of the covalently stabilized dimer HCC in solution by the small angle X-ray scattering (SAXS) technique and synchrotron radiation. Experimental data confirmed that in solution this protein forms a dimer, which is characterized by the radius of gyration RG = 3.1 nm and maximum intramolecular distance Dmax = 10.3 nm. Using the ab initio method and program DAMMIN, we propose a low resolution structure of stabilized covalently cystatin C in solution. Stab-HCC dimer adopts in solution an elongated conformation, which is well reconstructed by the ab initio model. © 2017 Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak20171,

title = {Proceedings of the XIII International School and Symposium on Synchrotron Radiation in Natural Science 2016, Ustroń-Jaszowiec, Poland},

author = {Maciej Kozak and Wojciech M. Kwiatek and Paweł Piszora},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029493618&doi=10.1016%2fj.nimb.2017.08.041&partnerID=40&md5=e8b60bd56f6263ec19da14339afa6c10},

doi = {10.1016/j.nimb.2017.08.041},

issn = {0168583X},

year  = {2017},

date = {2017-01-01},

journal = {Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms},

volume = {411},

pages = {1 – 3},

publisher = {Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Nowakowski2017121,

title = {Preliminary results of human PrPC protein studied by spectroscopic techniques},

author = {Michał Nowakowski and Joanna Czapla-Masztafiak and Maciej Kozak and Igor Zhukov and Lilia Zhukova and Jakub Szlachetko and Wojciech M. Kwiatek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85021284972&doi=10.1016%2fj.nimb.2017.06.022&partnerID=40&md5=cb303c6fdb03ee44b8dd9b352246ed1b},

doi = {10.1016/j.nimb.2017.06.022},

issn = {0168583X},

year  = {2017},

date = {2017-01-01},

journal = {Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms},

volume = {411},

pages = {121 – 128},

publisher = {Elsevier B.V.},

abstract = {Neurodegenerative diseases are one of the malfunctions of human nervous system, being a class of complex and prominent pathologies. The human prion Protease Resistant Protein (PrP) is protein regulating copper metabolism in mammalian cells through binding of Cu(II) ions to specific fragments. Nowadays misfolding of this protein is associated with development of prion diseases. Therefore, it is crucial to obtain structural information about coordination of Cu(II) by PrP protein. Herein, we report X-ray absorption spectroscopy (XAS) measurements, carried out on SuperXAS beamline (SLS, PSI Villigen) on PrPC-Cu(II) complexes. Obtained results were compared with theoretical predictions done by FEFF 9.6 software. Complementary to XAS data, Atomic Force Microscopy (AFM) measurements were conducted to obtain low resolution structural information about prepared sample that allow to develop protocol of fixing PrPC molecules on solid substrate used for further experiments. It has been established that folded C-terminal domain of PrPC protein has around 5 nm in diameter. Presented results showed that both XAS and AFM methods are useful tools in detailed examination of complexes of human PrPC either with Cu(II) or with other divalent metal ions. © 2017 Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Piosik201785,

title = {Structural studies of degradation process of zirconium dioxide tetragonal phase induced by grinding with dental bur},

author = {A. Piosik and K. Żurowski and Z. Pietralik and W. Hędzelek and M. Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026657915&doi=10.1016%2fj.nimb.2017.07.024&partnerID=40&md5=11e9a1737b28b35640486a5cc5299e1d},

doi = {10.1016/j.nimb.2017.07.024},

issn = {0168583X},

year  = {2017},

date = {2017-01-01},

journal = {Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms},

volume = {411},

pages = {85 – 93},

publisher = {Elsevier B.V.},

abstract = {Zirconium dioxide has been widely used in dental prosthetics. However, the improper mechanical treatment can induce changes in the microstructure of zirconium dioxide. From the viewpoint of mechanical properties and performance, the phase transitions of ZrO2 from the tetragonal to the monoclinic phase induced by mechanical processing, are particularly undesirable. In this study, the phase transitions of yttrium stabilized zirconium dioxide (Y-TZP) induced by mechanical treatment are investigated by the scanning electron microscopy (SEM), atomic force microscopy (AFM) and powder diffraction (XRD). Mechanical stress was induced by different types of drills used presently in dentistry. At the same time the surface temperature was monitored during milling using a thermal imaging camera. Diffraction analysis allowed determination of the effect of temperature and mechanical processing on the scale of induced changes. The observed phase transition to the monoclinic phase was correlated with the methods of mechanical processing. © 2017 Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Krȩcisz2016,

title = {Interactions between magnetic nanoparticles and model lipid bilayers - Fourier transformed infrared spectroscopy (FTIR) studies of the molecular basis of nanotoxicity},

author = {M. Krȩcisz and J. D. Rybka and A. J. Strugała and B. Skalski and M. Figlerowicz and M. Kozak and M. Giersig},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988728301&doi=10.1063%2f1.4962951&partnerID=40&md5=26c3a9e4cd5926b38038c7c90e5115e2},

doi = {10.1063/1.4962951},

issn = {00218979},

year  = {2016},

date = {2016-01-01},

journal = {Journal of Applied Physics},

volume = {120},

number = {12},

publisher = {American Institute of Physics Inc.},

abstract = {The toxicity of nanoparticles (nanotoxicity) is often associated with their interruption of biological membranes. The effect of polymer-coated magnetic nanoparticles (with different Fe3O4 core sizes and different polymeric coatings) on a model biological membrane system of vesicles formed by dimyristoylphosphatidylcholine (DMPC) was studied. Selected magnetic nanoparticles with core sizes ranging from 3 to 13 nm (in diameter) were characterised by transmission electron microscopy. Samples with 10% DMPC and different nanoparticle concentrations were studied by attenuated total reflectance - Fourier transform infrared spectroscopy to establish the influence of nanoparticles on the phase behaviour of model phospholipid systems. © 2016 Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Andrzejewska2016598,

title = {Structural studies of the formation of lipoplexes between siRNA and selected bis-imidazolium gemini surfactants},

author = {W. Andrzejewska and Z. Pietralik and M. Skupin and M. Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84978908841&doi=10.1016%2fj.colsurfb.2016.06.062&partnerID=40&md5=27b8e51bf60cde33b8f7dcd7e30af2ea},

doi = {10.1016/j.colsurfb.2016.06.062},

issn = {09277765},

year  = {2016},

date = {2016-01-01},

journal = {Colloids and Surfaces B: Biointerfaces},

volume = {146},

pages = {598 – 606},

publisher = {Elsevier B.V.},

abstract = {Dicationic (gemini) surfactants are agents that can be used for the preparation of stable complexes of nucleic acids, particularly siRNA for therapeutic purposes. In this study, we demonstrated that bis-imidazolium gemini surfactants with variable lengths of dioxyalkyl linker groups (from dioxyethyl to dioxydodecyl) and dodecyl side chains are excellent for the complexation of siRNA. All of these compounds effectively complexed siRNA in a charge ratio range (p/n) of 1.5–10. The low resolution structure of siRNA oligomers was characterised by small angle scattering of synchrotron radiation (SR-SAXS) and ab initio modelling. The structures of the formed complexes were also analysed using SR-SAXS, circular dichroism studies and electrophoretic mobility tests. The most promising agents for complexation with siRNA were the surfactants that contained dioxyethyl and dioxyhexyl spacer groups. © 2016 Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Skupin2016,

title = {The system with zwitterionic lactose-based surfactant for complexation and delivery of small interfering ribonucleic acid - A structural and spectroscopic study},

author = {Michalina Skupin and Krzysztof Sobczak and Ryszard Zieliński and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84971330201&doi=10.1063%2f1.4952589&partnerID=40&md5=34c8c79dd533979cab13708df8a5282d},

doi = {10.1063/1.4952589},

issn = {00036951},

year  = {2016},

date = {2016-01-01},

journal = {Applied Physics Letters},

volume = {108},

number = {21},

publisher = {American Institute of Physics Inc.},

abstract = {Systems suitable for the effective preparation of complexes with siRNA (small interfering RNA) are at the center of interest in the area of research work on the delivery of the RNA-based drugs (RNA-therapeutics). This article presents results of a study on the structural effects associated with siRNA complexation by a surfactant comprising a lactose group (N-(3-propanesulfone)-N-dodecyl-amino-beta-D-lactose hydrochloride, LA12). The double stranded siRNA oligomer (21 base pairs) used in this study is responsible for silencing a gene that can be important in the therapy of myotonic dystrophy type 1. The obtained siRNA/LA12 lipoplexes were studied using the methods of small angle scattering of synchrotron radiation, circular dichroism spectroscopy, Fourier transform infrared spectroscopy, and electrophoretic mobility tests. Lipoplexes form in solution stable lamellar or cubic phases. The surfactant selected for the study shows much lower cytotoxicity and good complexation abilities of siRNA than dicationic or polycationic surfactants. © 2016 Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pietralik20162424,

title = {Dicationic Surfactants with Glycine Counter Ions for Oligonucleotide Transportation},

author = {Zuzanna Pietralik and Andrzej Skrzypczak and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982987703&doi=10.1002%2fcphc.201600175&partnerID=40&md5=a10110f51619df47381c61d64496e7a4},

doi = {10.1002/cphc.201600175},

issn = {14397641},

year  = {2016},

date = {2016-01-01},

journal = {Chemphyschem : a European journal of chemical physics and physical chemistry},

volume = {17},

number = {15},

pages = {2424 – 2433},

abstract = {Gemini surfactants are good candidates to bind, protect, and deliver nucleic acids. Herein, the concept of amino acids (namely glycine) as counter ions of gemini surfactants for gene therapy application was explored. This study was conducted on DNA and RNA oligomers and two quaternary bis-imidazolium salts, having 2,5-dioxahexane and 2,8-dioxanonane spacer groups. The toxicity level of surfactants was assessed by an MTT assay, and their ability to bind nucleic acids was tested through electrophoresis. The nucleic acid conformation was established based on circular dichroism and infrared spectroscopic analyses. The structures of the formed complexes were characterized by small-angle scattering of synchrotron radiation. Both studied surfactants appear to be suitable for gene therapy; however, although they vary by only three methylene groups in the spacer, they differ in binding ability and toxicity. The tested oligonucleotides maintained their native conformations upon surfactant addition and the studied lipoplexes formed a variety of structures. In systems based on a 2,5-dioxahexane spacer, a hexagonal phase was observed for DNA-surfactant complexes and a micellar phase was dominant with RNA. For the surfactant with a 2,8-dioxanonane spacer group, the primitive cubic phase prevailed. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Balcerzak2015108,

title = {Adsorption of dimeric surfactants in lamellar silicates},

author = {Mateusz Balcerzak and Zuzanna Pietralik and Ludwik Domka and Andrzej Skrzypczak and MacIej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84955413660&doi=10.1016%2fj.nimb.2015.07.135&partnerID=40&md5=eb495c939474c8696b2aa985b2dbe14f},

doi = {10.1016/j.nimb.2015.07.135},

issn = {0168583X},

year  = {2015},

date = {2015-01-01},

journal = {Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms},

volume = {364},

pages = {108 – 115},

publisher = {Elsevier},

abstract = {The adsorption of different types of cationic surfactants in lamellar silicates changes their surface character from hydrophilic to hydrophobic. This study was undertaken to obtain lamellar silicates modified by a series of novel dimeric (gemini) surfactants of different length alkyl chains and to characterise these organophilised materials. Synthetic sodium montmorillonite SOMASIF® ME 100 (M) and enriched bentonite of natural origin (Nanoclay - hydrophilic bentonite®) were organophilised with dimeric (gemini) surfactants (1,1′-(1,4-butanediyl)bis(alkoxymethyl)imidazolium dichlorides). As a result of surfactant molecule adsorption in interlamellar space, the d-spacing (d 001) increased from 0.97 nm (for the anhydrous structure) to 2.04 nm. A Fourier transform infrared spectroscopy (FTIR) analysis of the modified systems reveals bands assigned to the stretching vibrations of the CH2 and CH3 groups and the scissoring vibrations of the NH group from the structure of the dimeric surfactants. Thermogravimetric (TG) and derivative thermogravimetric (DTG) studies imply a four-stage process of surfactant decomposition. Scanning electron microscopy (SEM) images provide information on the influence of dimeric surfactant intercalation into the silicate structures. Particles of the modified systems show a tendency toward the formation of irregularly shaped agglomerates. © 2015 Elsevier B.V. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pietralik201583,

title = {The influence of novel gemini surfactants containing cycloalkyl side-chains on the structural phases of DNA in solution},

author = {Zuzanna Pietralik and Janet R. Kumita and Christopher M. Dobson and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84928956787&doi=10.1016%2fj.colsurfb.2015.04.042&partnerID=40&md5=29034adcb67fef8da9d8e5eb0695510f},

doi = {10.1016/j.colsurfb.2015.04.042},

issn = {09277765},

year  = {2015},

date = {2015-01-01},

journal = {Colloids and Surfaces B: Biointerfaces},

volume = {131},

pages = {83 – 92},

publisher = {Elsevier},

abstract = {Very important to gene therapy is the delivery system of the nucleic acids (called a vector), which will enhance the efficiency of the transport of new DNA into cells whilst protecting against damage. A promising alternative to the currently used viral vectors are the systems based on amphiphilic compounds - lipoplexes. Among them, gemini surfactants, which consist of two hydrophobic chains and two cationic heads connected by a linker - spacer group, appear to be promising candidates. The subject of this study involves two gemini surfactants, alkoxy derivatives of bis-imidazolium quaternary salts, differing in the length of their spacer groups and how they interact with two types of salmon sperm DNA (low and high molecular weight (MW)) or plasmid DNA (pDNA). The mixtures of gemini surfactants with nucleic acids of differing p/. n ratios (positive-to-negative charge ratio) were characterised by small angle X-ray scattering (SAXS) of synchrotron radiation, dynamic light scattering (DLS), circular dichroism (CD) spectroscopy, atomic force microscopy (AFM), transmission electron microscopy (TEM) and gel electrophoresis techniques. This analysis allows for the selection of the most suitable and promising candidates for non-viral vectors in gene therapy, determination of the conditions needed to form stable complexes, identification of conformational changes in the DNA molecules upon interactions with gemini surfactants and in some cases, determination of the structures formed in these lipoplexes. © 2015 Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak20151,

title = {12th International School and Symposium on Synchrotron Radiation in Natural Sciences (ISSRNS 2014)},

author = {Maciej Kozak and Wojciech M. Kwiatek and Bogdan Kowalski},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028202722&doi=10.1016%2fj.nimb.2015.09.063&partnerID=40&md5=3233a712497d41b8fd774417d80d884f},

doi = {10.1016/j.nimb.2015.09.063},

issn = {0168583X},

year  = {2015},

date = {2015-01-01},

journal = {Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms},

volume = {364},

pages = {1 – 3},

publisher = {Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kwiatek20131,

title = {SOLARIS: Waiting for the first light-Proceedings of XI International School and Symposium on Synchrotron Radiation in Natural Science 2012, Kraków, Poland},

author = {Wojciech M. Kwiatek and Maciej Kozak and Wojciech Paszkowicz},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885485907&doi=10.1016%2fj.radphyschem.2013.08.003&partnerID=40&md5=1d0c6cf6587e150a94b8eba312f2c272},

doi = {10.1016/j.radphyschem.2013.08.003},

issn = {18790895},

year  = {2013},

date = {2013-01-01},

journal = {Radiation Physics and Chemistry},

volume = {93},

pages = {1 – 3},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zienkiewicz-Strzałka2013337,

title = {Silver nanoparticles incorporated onto ordered mesoporous silica from Tollen's reagent},

author = {M. Zienkiewicz-Strzałka and S. Pasieczna-Patkowska and M. Kozak and S. Pikus},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84872807677&doi=10.1016%2fj.apsusc.2012.12.021&partnerID=40&md5=411cab53baa5d034c3ee69d12c646bf6},

doi = {10.1016/j.apsusc.2012.12.021},

issn = {01694332},

year  = {2013},

date = {2013-01-01},

journal = {Applied Surface Science},

volume = {266},

pages = {337 – 343},

publisher = {Elsevier B.V.},

abstract = {Noble metal nanostructures supported on mesoporous silica are bridge between traditional silica adsorbents and modern catalysts. In this work the Ag/SBA-15 mesoporous materials were synthesized and characterized. Various forms of nanosilver supported on ordered mesoporous template have been successfully obtained via proposed procedures. In all synthesized materials, Tollen's reagent (diammine silver complex [Ag(NH 3 ) 2 ] + ) was used as a silver source. Silver nanoparticles were prepared by reduction of ammoniacal silver complex by formaldehyde in the solution of stabilizer. After reduction, Ag nanoparticles could be deposited on SBA-15, or added during traditional synthesis of SBA-15 giving silver or silver chloride nanoparticles in the combination with porous silica. Silver nanostructures as nanoparticles or nanowires were also embedded onto the SBA-15 by incipient wetness impregnation of silver ions. Absorbed silver ions were next reduced under hydrogen at high temperature. There are many advantages of utilized ammoniacal silver complex as a silver source. Proposed method is capable to synthesis of various metal nanostructures with controlled composition and morphology. The silver ammonia complex is composed of two ions surrounding and protecting the central silver ion, so it is possible to obtain very small nanoparticles using simple approach without any functionalization of external and internal surface of SBA-15. This approach allows obtaining greatly small silver nanoparticles on SBA-15 (4 nm) or nanowires depending on the metal loading amount. Moreover, the colloidal silver solution prepared from Tollen's reagent, in the presence of triblock copolymer, remains stable for a long time. Reduction of Tollen's reagent to silver colloidal solution seems to be efficient, fast and interesting approach for the preparation of supported silver nanostructures Obtained samples were characterized by powder X-ray diffraction, small angle X-ray scattering (SAXS), UV-vis spectroscopy, transmission electron microscopy (TEM), nitrogen adsorption-desorption isotherms and photoacoustic spectroscopy (PAS). © 2012 Elsevier B.V. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Murawska2013160,

title = {The structure and morphology of gold nanoparticles produced in cationic gemini surfactant systems},

author = {Magdalena Murawska and Michalina Wiatr and Paweł Nowakowski and Kosma Szutkowski and Andrzej Skrzypczak and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885870746&doi=10.1016%2fj.radphyschem.2013.05.024&partnerID=40&md5=129e3cb4d61f1cfba487a101bb8f267f},

doi = {10.1016/j.radphyschem.2013.05.024},

issn = {18790895},

year  = {2013},

date = {2013-01-01},

journal = {Radiation Physics and Chemistry},

volume = {93},

pages = {160 – 167},

abstract = {Potential applications of gold nanoparticles (GNP) are strictly connected with their size and shape. The influence of different dicationic (gemini) surfactants, alkyloxymethylimidazolium derivatives derivatives, on the structure and morphology of GNP was studied. The synthesis of nanoparticles was performed in the presence of various gemini surfactants-dodecyloxymethylimidazolium nitrate (IMI_NO3_C4_C12), propionate (IMI_PROP_C4_C12) and 3,3'-[1,9-(2,8-dioxanonane)]bis-(1-nonyloxymethylimidazolium) chloride (IMI_Cl_oxyC7_C9), used as stabilizers and templates for obtaining different size and shape of gold nanoparticles. The samples obtained were examined using transmission electron microscopy (TEM), small angle scattering of synchrotron radiation (SAXS), UV-vis spectroscopy and NMR PFG spectroscopy. For the obtained solutions of nanoparticles the plasmon resonance was observed at the wavelengths corresponding to the presence of gold nanoparticles of sizes ranging from 5-100. nm, with a significant shift towards higher wavelength for the samples prepared with addition of dicationic surfactants. TEM images evidence the presence of gold nanoparticles with tetrahedral and spherical morphology in solutions prepared with the surfactants IMI_PROP_C4_C12, IMI_NO3_C4_C12, and those of spherical morphology, but strongly aggregated, in the solution with the cationic surfactant IMI_Cl_oxyC7_C9. © 2013 Elsevier Ltd.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Marciniec20132165,

title = {Analytical study on irradiated methylxanthine derivatives},

author = {Barbara Marciniec and Maciej Stawny and Karol Olszewski and Maciej Kozak and Marek Naskrent},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84881479149&doi=10.1007%2fs10973-012-2774-8&partnerID=40&md5=55505ad82f36b5b108aa938d236d8b2c},

doi = {10.1007/s10973-012-2774-8},

issn = {13886150},

year  = {2013},

date = {2013-01-01},

journal = {Journal of Thermal Analysis and Calorimetry},

volume = {111},

number = {3},

pages = {2165 – 2170},

abstract = {The effect of ionising radiation on the physico-chemical properties of three derivatives of xanthine: caffeine, theophylline and theobromine, has been studied. The above-drugs in the solid phase have been irradiated with E-beam of the energy 9.96 MeV with the doses varied from 25 to 400 kGy. The effects of the irradiation have been examined by differential scanning calorimetry (DSC), electron paramagnetic resonance (EPR) and high-performance liquid chromatography (HPLC). The results have shown that the methylxanthine derivatives studied are resistant to ionising irradiation in the doses usually used for sterilisation (<50 kGy), which means that they are relatively radiochemically stable and can be sterilised by irradiation. © 2012 The Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wypych2013212,

title = {Interactions of a cationic surfactant - (benzyloxymethyl) dodecyldimethylammonium chloride with model biomembrane systems},

author = {Aleksandra Wypych and Kamil Szpotkowski and Stefan Jurga and Ludwik Domka and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84876342625&doi=10.1016%2fj.colsurfb.2013.03.010&partnerID=40&md5=1af9e51b4c74a315272cac3ffa370c99},

doi = {10.1016/j.colsurfb.2013.03.010},

issn = {18734367},

year  = {2013},

date = {2013-01-01},

journal = {Colloids and Surfaces B: Biointerfaces},

volume = {108},

pages = {212 – 218},

abstract = {Phospholipids are the main components of biological membranes. The aim of the present study was to determine the influence of a cationic surfactant on phospholipid structure and dynamics. Fourier transform infrared (FTIR) and dielectric relaxation (DRS) spectroscopies as well as small-angle X-ray scattering (SAXS) with synchrotron radiation have been used to analyse the structure of fully hydrated 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) in the presence of a quaternary ammonium surfactant: (benzyloxymethyl) dodecyldimethylammoniumchloride (BzMDDAC). The presence of the surfactant caused changes in the temperature of the DMPC phase transition, as revealed using FTIR and DRS measurements. This change results from the disappearance of the multilamellar phase of DMPC and the formation of the unilamellar (most likely bicellar) phase, as indicated by the SAXS results. © 2013 Elsevier B.V.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Marciniec201233,

title = {DSC and spectroscopic studies of disulfiram radiostability in the solid state},

author = {Barbara Marciniec and Katarzyna Dettlaff and Marek Naskrent and Zuzanna Pietralik and MacIej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84858075287&doi=10.1007%2fs10973-011-1810-4&partnerID=40&md5=b3db4edda48bdf0477829bde5c7fd2fa},

doi = {10.1007/s10973-011-1810-4},

issn = {13886150},

year  = {2012},

date = {2012-01-01},

journal = {Journal of Thermal Analysis and Calorimetry},

volume = {108},

number = {1},

pages = {33 – 40},

abstract = {The effect of ionising radiation on the physico-chemical properties of disulfiram (Antabuse, Esperal, bisdiethylthiocarbamoil disulphide) has been studied by DSC, FTIR, EPR, MS, TLC and HPLC. Sterilisation was carried out in the solid state, at room temperature and normal air humidity using the electron beam of 9.96 Mev from accelerator. All the measurements were made simultaneously for the irradiated and nonirradiated substance. It has been found that the drug studied in solid phase when subjected to an electron beam corresponding to the irradiation in the doses 10-100 kGy shows the presence of free radicals (EPR), and a change in colour from white to pale green-grey that disappears after solution in water or methanol. After the irradiation with the dose of 100 kGy, its melting point and enthalpy slightly decreased. Also the content of the active substance decreases (HPLC -1.5%, UV -3.6%, iodometric titration method -2.7%) and trace amounts of the radiolysis products appear (HPLC). The substance irradiated with the doses 10-50 kGy does not show changes in the melting point, in the content and presence of the radiolysis products. The EPR results have shown that free radicals disappear after about a year and the discolouring disappears with them. The results of this study have shown that disulfiram can be subjected to sterilisation by irradiation with no deterioration of its physico-chemical properties, but a long time of storage needed to remove free radicals and discolouration questions the economic justification for this type of sterilisation. © 2011 The Author(s).},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kida2012893,

title = {Structural changes of DPPC bilayers induced by gemini surfactant},

author = {W. Kida and M. Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84860324864&doi=10.12693%2fAPhysPolA.121.893&partnerID=40&md5=c279b465cc0f6b7dcc6d73ed110a2fee},

doi = {10.12693/APhysPolA.121.893},

issn = {05874246},

year  = {2012},

date = {2012-01-01},

journal = {Acta Physica Polonica A},

volume = {121},

number = {4},

pages = {893 – 898},

publisher = {Polish Academy of Sciences},

abstract = {The phospholipid-gemini surfactant systems are promising agents for construction of lipoplexes for DNA delivery systems in gene therapy. In this work the influence of a gemini surfactant - 1,1′-(1,6-hexan)bis3- octyloxymethylimidazolium di-chloride) (IMI-Cl-C6-C8) on the structure and phase behaviour of aqueous suspensions of the fully hydrated phospholipid - 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) were characterised using small angle scattering of synchrotron radiation (SAXS), differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR). The surfactant studied caused a destabilisation of the lamellar phase typical of DPPC. Addition of the surfactant also shifted to lower temperatures and extended the range of the main phase transition.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Murawska2012888,

title = {Structure and morphology of gold nanoparticles in solution studied by TEM, SAXS and UV-Vis},

author = {M. Murawska and A. Skrzypczak and M. Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84860328987&doi=10.12693%2fAPhysPolA.121.888&partnerID=40&md5=d6ee008a6dc4653af70f47edf5bbbcdb},

doi = {10.12693/APhysPolA.121.888},

issn = {05874246},

year  = {2012},

date = {2012-01-01},

journal = {Acta Physica Polonica A},

volume = {121},

number = {4},

pages = {888 – 892},

publisher = {Polish Academy of Sciences},

abstract = {Gold nanoparticles have a great number of applications, among others in material sciences, biology and medicine. A method for the synthesis of gold nanoparticles in solution with the use of gemini surfactant was proposed and the nanoparticles obtained were subjected to thorough characterisation. The method proposed is a modification of the Turkevich method, based on reduction of tetrachloroauric acid in the presence of trisodium citrate and a dicationic (gemini) surfactant - 1,1′-(1,4-butan)bis(3-dodecyloxymethylimidazolium) di-propionate. Morphology and size distribution of gold nanoparticles obtained were examined by the transmission electron microscopy (TEM), UV-Vis spectroscopy and small angle scattering of synchrotron radiation (SAXS). The plasmon resonance of the nanoparticles obtained was observed in the wavelength range corresponding to the presence of gold nanoparticles with sizes ranging from 5 to 100 nm. TEM images confirmed that the spherical shape of nanoparticles was dominated in reference solutions prepared of sodium citrate and tetrachloroauric acid. In the solutions prepared with addition of gemini surfactant, the gold nanoparticles of triangular morphology were observed.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2011999,

title = {Synchrotron radiation studies in Poland-The 10th International School and Symposium on Synchrotron Radiation in Natural Science (ISSRNS)},

author = {Maciej Kozak and Wojciech Paszkowicz and Paweł Piszora},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-79960248311&doi=10.1016%2fj.radphyschem.2011.06.003&partnerID=40&md5=c4d91debb15e95f0dfefd3b2023e46a8},

doi = {10.1016/j.radphyschem.2011.06.003},

issn = {18790895},

year  = {2011},

date = {2011-01-01},

journal = {Radiation Physics and Chemistry},

volume = {80},

number = {10},

pages = {999 – 1000},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2010747,

title = {Structural and spectroscopic studies of DMPC/cationic surfactant system},

author = {Maciej Kozak and Aleksandra Wypych and Kamil Szpotkowski and Stefan Jurga and Andrzej Skrzypczak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77349111495&doi=10.1016%2fj.jnoncrysol.2009.07.043&partnerID=40&md5=b5558bee013813ca582186ddc7f48ede},

doi = {10.1016/j.jnoncrysol.2009.07.043},

issn = {00223093},

year  = {2010},

date = {2010-01-01},

journal = {Journal of Non-Crystalline Solids},

volume = {356},

number = {11-17},

pages = {747 – 753},

abstract = {Aqueous suspension of a mixture of 1,2-dimyrilstoyl-sn-glycero-3-phosphocholine (DMPC) and (dodecyloxymethyl)dodecydimethylammonium (DDMDDAC) has been investigated by Fourier transform infrared spectroscopy (FTIR), small angle scattering of synchrotron radiation (SAXS) and dielectric spectroscopy (DS). The introduction of surfactant to DMPC water solution probably induces formation of discoidal (bicellar) phase, as revealed by SAXS studies. The presence of the surfactant has been found to decrease the main phase transition temperature, i.e., from rippled gel to liquid crystalline phase, as indicated by the DS and FTIR results. The small steps in the real part of dielectric permittivity plot vs. temperature can be related to the: planar gel to rippled gel (Lβ′ →Pβ′ ) and rippled gel-liquid crystal (Pβ′ → Lα) phase transitions, which is supported by the temperature dependencies of the symmetric and anti-symmetric CH2 band frequencies from FTIR measurements. © 2010 Elsevier B.V. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Taube2010307,

title = {Low resolution structure of RARl-GST-tag fusion protein in solution},

author = {M. Taube and A. Jarmolowski and M. Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77949356185&doi=10.12693%2fAPhysPolA.117.307&partnerID=40&md5=5a78f466bb10aaf3bf5d69ef8727e59b},

doi = {10.12693/APhysPolA.117.307},

issn = {05874246},

year  = {2010},

date = {2010-01-01},

journal = {Acta Physica Polonica A},

volume = {117},

number = {2},

pages = {307 – 310},

publisher = {Polish Academy of Sciences},

abstract = {RARl is a protein required for resistance mediated by many R genes and function upstream of signaling pathways leading to H2O2 accumulation. The structure and conformation of RARl-GST-Tag fusion protein from barley (Hordeum vulgare) in solution was studied by the small angle scattering of synchrotron radiation. It was found that the dimer of RARl-GST-Tag protein is characterized in solution by radius of gyration RG = 6.19 nm and maximal intramolecular vector Dmax = 23 nm. On the basis of the small angle scattering of synchrotron radiation SAXS data two bead models obtained by ab initio modeling are proposed. Both models show elongated conformations. We also concluded that molecules of fusion protein form dimers in solution via interaction of GST domains.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pietralik2010311,

title = {SAXS study of influence of gemini surfactant, 1, 1′- ( 1, 4-butanediyl) bis 3-cyclododecyloxymethylimidazolium di-chloride, on the fully hydrated DMPC},

author = {Z. Pietralik and M. Taube and A. Skrzypczak and M. Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77949401300&doi=10.12693%2fAPhysPolA.117.311&partnerID=40&md5=f1ba356946b5293e3d9a5886ae9c3e11},

doi = {10.12693/APhysPolA.117.311},

issn = {05874246},

year  = {2010},

date = {2010-01-01},

journal = {Acta Physica Polonica A},

volume = {117},

number = {2},

pages = {311 – 314},

publisher = {Polish Academy of Sciences},

abstract = {The study has been performed on model systems of biological membranes obtained on the basis of l,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and cationic gemini surfactant -derivative of 1,1′-(1,4-butane)bis 3-alkyloxymethylimidazolium chlorides with cyclic chains. The small angle X-ray scattering SAXS results implied a gradual disappearance (as a function of surfactant concentration) of the lamellar phase typical of DMPC and formation of unilamellar phase -probably a bicellar phase.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Marciniec2010261,

title = {DSC and EPR analysis of some radiation sterilized alkaloids},

author = {B. Marciniec and M. Kozak and M. Naskrent and M. Hofman and K. Dettlaff and M. Stawny},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649721368&doi=10.1007%2fs10973-009-0445-1&partnerID=40&md5=7567184a46a1e8dab46d1bfde413db12},

doi = {10.1007/s10973-009-0445-1},

issn = {13886150},

year  = {2010},

date = {2010-01-01},

journal = {Journal of Thermal Analysis and Calorimetry},

volume = {102},

number = {1},

pages = {261 – 267},

abstract = {The effect of ionising radiation on the physicochemical properties of salts of three alkaloids has been studied: codeine phosphate (COD), papaverine hydrochloride (PAP) and pilocarpine hydrochloride (PIL). These compounds in the solid state were irradiated with an e-beam of the energy of 9.96 MeV to achieve doses ranging from 25 to 400 kGy, and then they were subjected to organoleptic analysis, thermal analysis (differential scanning calorimetry, DSC), electron resonance (EPR) spectroscopy, scanning electron microscopy observations and X-ray diffraction study. The most informative were the results provided by the EPR and DSC methods. The EPR spectra revealed the presence of long-lived radicals whose concentration was directly proportional to the dose of irradiation for all the compounds studied. (PIL 2.14 × 1016 spin/g,.COD 6.85 × 1015 spin/g, PAP 2.50 × 10 14 spin/g-for the dose of 100 kGy). The DSC results revealed a decrease in the melting point by 5.9 °C for COD and by 0.8 °C for PIL after irradiation with 200 kGy, which is indicative of products of radiolysis, of which at least one is non-white, and changes the colour of the compounds. PAP, for which no decrease in the melting point and no colour change was observed and for which the concentration of free radicals was the lowest, was found to be most stable from among the compounds studied. It will probably be suitable for radiation sterilisation. The other two compounds COD and PIL show much lower radiochemical stability and should be subjected to more detailed examination to establish the mechanism of radiolysis and the possibility of radiation sterilisation. Our results have confirmed the earlier reports on high radiochemical stability of PAP, but do not confirm the resistance to ionising radiation of COD and PIL. COD 6.85 × 1015 spin/g, PAP 2.50 × 1014 spin/g-for the dose of 100 kGy). The DSC results revealed a decrease in the melting point by 5.9 °C for COD and by 0.8 °C for PIL after irradiation with 200 kGy, which is indicative of products of radiolysis, of which at least one is non-white, and changes the colour of the compounds. PAP, for which no decrease in the melting point and no colour change was observed and for which the concentration of free radicals was the lowest, was found to be most stable from among the compounds studied. It will probably be suitable for radiation sterilisation. The other two compounds COD and PIL show much lower radiochemical stability and should be subjected to more detailed examination to establish the mechanism of radiolysis and the possibility of radiation sterilisation. Our results have confirmed the earlier reports on high radiochemical stability of PAP, but do not confirm the resistance to ionising radiation of COD and PIL. © 2009 Akadémiai Kiadó, Budapest, Hungary.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pikus20105311,

title = {Studies of intrawall porosity in the hexagonally ordered mesostructures of SBA-15 by small angle X-ray scattering and nitrogen adsorption},

author = {Stanislaw Pikus and Ewa B. Celer and Mietek Jaroniec and Leonid A. Solovyov and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-77953135465&doi=10.1016%2fj.apsusc.2009.12.068&partnerID=40&md5=98ca6f3f74b0a3b395803d0a35a8837d},

doi = {10.1016/j.apsusc.2009.12.068},

issn = {01694332},

year  = {2010},

date = {2010-01-01},

journal = {Applied Surface Science},

volume = {256},

number = {17},

pages = {5311 – 5315},

publisher = {Elsevier},

abstract = {Ordered mesoporous silicas (OMSs) such as SBA-15 (p6mm symmetry group) synthesized in the presence of block copolymers containing poly(ethylene oxide) blocks possess irregular complementary pores in the walls of ordered mesopores. The X-ray scattering caused by this complementary porosity contributes to the background of the SAXS patterns. This work shows the possibility of using the SAXS data for the study of intrawall channels interconnecting ordered cylinders in SBA-15. The proposed SAXS analysis was tested by using a series of SBA-15 samples obtained at different temperatures of hydrothermal treatment (from 60 to 180 °C). The structural modelling of the SAXS patterns recorded for a series of SBA-15 samples was performed by using the continuous density function (CDF) technique in combination with the derivative difference minimization (DDM) method of full-profile refinement. This method is well suited for extraction of the background curves from the SAXS patterns. The resulting smooth background curves were analyzed by the well-known method in the SAXS theory used for evaluation of heterogeneity distributions, which in this case characterize the intrawall complementary porosity. A relatively good agreement has been observed between the data obtained by SAXS and nitrogen adsorption analysis. The SAXS analysis is sufficiently sensitive for examination of heterogeneous microporosity in SBA-15 materials. The average diameter of intrawall pores for the SBA-15 sample obtained at 60 °C was only about 1.4 nm. However, this diameter increased with the increasing temperature of hydrothermal treatment; namely, it was 1.5, 1.8, 2.6, 2.6, 3.5 and 5.2 nm for the SBA-15 samples hydrothermally treated at 80, 100, 120, 140, 160 and 180 °C, respectively. © 2009 Elsevier B.V. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Barczak2010457,

title = {Studies of the structure and chemistry of SBA-15 organosilicas functionalized with amine, thiol, vinyl and phenyl groups},

author = {Mariusz Barczak and Andrzej Da̧browski and Stanislaw Pikus and Janusz Ryczkowski and Piotr Borowski and Maciej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649447919&doi=10.1007%2fs10450-010-9250-1&partnerID=40&md5=3a109d9f82eb47947cb71783a3374259},

doi = {10.1007/s10450-010-9250-1},

issn = {09295607},

year  = {2010},

date = {2010-01-01},

journal = {Adsorption},

volume = {16},

number = {4-5},

pages = {457 – 463},

abstract = {SBA-15 organosilicas containing amine, thiol, vinyl and phenyl pendant groups were synthesized by cocondensation of tetraethoxysilane and appropriate alkoxysilanes in the presence of Pluronic P123 surfactant. The obtained materials have usually well-developed porous structure-values of specific surface area are in the range 820-950 m2/g. Sizes of the ordered mesopores are in the range 7.5-9.1 nm while the interconnecting pores are 2.3- 3.1 nm in size. It was establish that size of the mesopores strongly depends even on small amounts of co-monomers co-condensing with tetraethoxysilane. Several instrumental techniques such as infrared spectroscopy, X-ray diffraction, nitrogen sorption measurements, elemental analysis, transmission electron microscopy. FT-IR photoacoustic spectroscopy (FT-IR/PAS) was used to determine chemical composition of the final materials and to monitor the efficiency of the template removal. © The Author(s) 2010.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2009S112,

title = {The effect of selected zwitterionic surfactant on the structure of hydrated DMPC},

author = {Maciej Kozak and Kamil Szpotkowski and Anna Kozak and Ryszard Zieliński and Daria Wieczorek and Michał J. Gajda},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-69249209664&doi=10.1016%2fj.radphyschem.2009.04.029&partnerID=40&md5=2203a1eea70f8188b4e8ee99ff2a4c31},

doi = {10.1016/j.radphyschem.2009.04.029},

issn = {0969806X},

year  = {2009},

date = {2009-01-01},

journal = {Radiation Physics and Chemistry},

volume = {78},

number = {10 SUPPL.},

pages = {S112–S115},

abstract = {Differential scanning calorimetry, Fourier transformed infrared (FTIR) spectroscopy and small angle scattering of synchrotron radiation have been used to analyse the influence of zwitterionic surfactant (3-(N-hexylmorpholine)-1-propansulfonate) on the conformational dynamics of CH2 and CH3 groups of 1,2-dimyrilstoyl-sn-glycero-3-phosphocholine (DMPC) and the phase behaviour of phospholipid bilayers. The surfactant causes changes in the DMPC phase transition temperature and promotes a gradual disappearance of the lamellar phase of DMPC and a probable formation of the bicellar phase. © 2009 Elsevier Ltd. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Szpotkowski2009561,

title = {Structural studies of selected DSPC-surfactant model systems of biological membranes},

author = {K. Szpotkowski and M. Kozak and A. Kozak and R. Zieliński and D. Wieczorek and S. Jurga},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-63549145837&doi=10.12693%2fAPhysPolA.115.561&partnerID=40&md5=14b787459b94847ec03d5580b626d6b7},

doi = {10.12693/APhysPolA.115.561},

issn = {05874246},

year  = {2009},

date = {2009-01-01},

journal = {Acta Physica Polonica A},

volume = {115},

number = {2},

pages = {561 – 564},

publisher = {Polish Academy of Sciences},

abstract = {Fourier transform infrared spectroscopy was used to analyse the influence of a cationic surfactant from the group of morpholine derivatives on the conformational dynamics of CH2 group in acyl chain of DSPC. The presence of the surfactant causes a decrease in the DSPC phase transition temperature. This result suggests that the surfactant interactions with phospholipid molecules disturb the lipid layers. The Fourier transform infrared measurements were supplemented with tests of the environmental toxicity of the surfactant used.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2009S134,

title = {Synchrotron radiation small angle scattering studies of d(TTAGGG)4 oligomer in solution},

author = {Maciej Kozak and Agnieszka Wlodarczyk and Andrzej Dobek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-69049084457&doi=10.1016%2fj.radphyschem.2009.04.028&partnerID=40&md5=0da2dc8ef3a91439453062b336490da8},

doi = {10.1016/j.radphyschem.2009.04.028},

issn = {0969806X},

year  = {2009},

date = {2009-01-01},

journal = {Radiation Physics and Chemistry},

volume = {78},

number = {10 SUPPL.},

pages = {S134–S136},

abstract = {Telomeric DNA sequences play a crucial role in maintaining chromosome stability and integrity. In human chromosomes telomeres are composed of tandem (TTAGGG)n repeats. The structural parameters and low-resolution structure of a synthetic d(TTAGGG)4 oligomer in solution has been studied in the absence and in the presence of potassium cations, with the use of the small angle scattering of synchrotron radiation. The radii of gyration RG, calculated for d(TTAGGG)4 oligomer (in 10 mM Tris/HCl pH 7.3) was 1.42 nm, while RG, (in 10 mM Tris/HCl pH 7.3; 0.1 mM KCl) was 1.32 nm. The pair distance distribution function, P(r), yielded a maximum dimension of 4.55and 4.35 nm for solutions in the absence and the presence of potassium cations. On the basis of SAXS data, the low-resolution structure in solution has been reconstructed using ab inito methods. © 2009 Elsevier Ltd. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2009S129,

title = {The FTIR and SAXS studies of influence of a morpholine derivatives on the DMPC-based biological membrane systems},

author = {Maciej Kozak and Kamil Szpotkowski and Anna Kozak and Ryszard Zieliński and Daria Wieczorek and Michał J. Gajda and Ludwik Domka},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-69249229485&doi=10.1016%2fj.radphyschem.2009.03.090&partnerID=40&md5=82193f3d500e443be825cd2beb46d990},

doi = {10.1016/j.radphyschem.2009.03.090},

issn = {0969806X},

year  = {2009},

date = {2009-01-01},

journal = {Radiation Physics and Chemistry},

volume = {78},

number = {10 SUPPL.},

pages = {S129–S133},

abstract = {Fourier transformed infrared (FTIR) spectroscopy and small-angle scattering of synchrotron radiation have been used to analyze the influence of two zwitterionic surfactants of the sulfobetaine structure (3-(N-decylmorpholine)-1-propansulfonate and 3-(N-tetradecylmorpholine)-1-propansulfonate) on the conformational dynamics of CH2 and O-P-O groups of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and the structure of phospholipid bilayers. The presence of the surfactant causes changes in the DMPC phase transition temperature. Our small-angle X-ray scattering (SAXS) data analysis implies a gradual disappearance of the lamellar phase typical of DMPC and a probable formation of the bicellar phase or cubic phase in DMPC/surfactants system. © 2009 Elsevier Ltd. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Kozak2009S125,

title = {SAXS-WAXS studies of the low-resolution structure in solution of xylose/glucose isomerase from Streptomyces rubiginosus},

author = {Maciej Kozak and Michał Taube},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-69049088711&doi=10.1016%2fj.radphyschem.2009.03.085&partnerID=40&md5=f4a7f3387de9e6cde70be14172369d2d},

doi = {10.1016/j.radphyschem.2009.03.085},

issn = {0969806X},

year  = {2009},

date = {2009-01-01},

journal = {Radiation Physics and Chemistry},

volume = {78},

number = {10 SUPPL.},

pages = {S125–S128},

abstract = {The structure and conformation of molecule of xylose/glucose isomerase from Streptomyces rubiginosus in solution (at pH 6 and 7.6; with and without the substrate) has been studied by small- and wide-angle scattering of synchrotron radiation (SAXS-WAXS). On the basis of the SAXS-WAXS data, the low-resolution structure in solution has been reconstructed using ab inito methods. A comparison of the models of glucose isomerase shows only small differences between the model in solution and the crystal structure. © 2009 Elsevier Ltd. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Marczewski2009300,

title = {Study of structure properties of organized silica sorbents synthesized on polymeric templates},

author = {Adam W. Marczewski and Anna Derylo-Marczewska and Iwona Skrzypek and Stanislaw Pikus and MacIej Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-67349140872&doi=10.1007%2fs10450-009-9183-8&partnerID=40&md5=058e849f8e6ca9fd6077f75b122c9137},

doi = {10.1007/s10450-009-9183-8},

issn = {09295607},

year  = {2009},

date = {2009-01-01},

journal = {Adsorption},

volume = {15},

number = {3},

pages = {300 – 305},

abstract = {Mesoporous silica materials were synthesized by applying Pluronic type polymers as pore creating agents. The composition of a reacting mixture and the process conditions were changed in a synthesis procedure. These changes differentiated the characteristics of porous structure of obtained sorbents. The parameters characterizing the pore structure were estimated and the changes of pore arrangement of obtained materials being a result of different synthesis conditions were investigated. The small-angle XRD results indicate that F cubic structure was formed what confirms the cage-like ordering of the synthesized silicas. © 2009 Springer Science+Business Media, LLC.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Marciniec2008865,

title = {The influence of radiation sterilization on thiamphenicol},

author = {B. Marciniec and M. Stawny and M. Kozak and M. Naskrent},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-43049116156&doi=10.1016%2fj.saa.2007.05.038&partnerID=40&md5=be557d7529fe9f8a33e846d319603b22},

doi = {10.1016/j.saa.2007.05.038},

issn = {13861425},

year  = {2008},

date = {2008-01-01},

journal = {Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy},

volume = {69},

number = {3},

pages = {865 – 870},

abstract = {The effect of ionising radiation, applied in the form of an electron beam, in the doses of 25, 100 and 400 kGy on the physical and chemical properties of thiamphenicol in solid phase has been studied by organoleptic analysis (form, colour, smell, solubility, clarity) and spectroscopic methods (UV, IR, EPR), chromatography (TLC), SEM observations, X-ray diffraction, polarimetry and thermal method (DSC). The above-discussed results have proved that on irradiation with a dose of 25 kGy no significant changes appear in thiamphenicol, apart from the formation of free radicals of the lifetime of over 352 days. On irradiation with much higher doses (100 and 400 kGy) no changes were observed in the IR spectra but the UV line intensities slightly increased at λmax = 266 and 273 nm, the colour of the powder changed, the radiolysis products appeared as detected by TLC, changes were also observed in the XRD, SEM pictures, the melting point values (DSC) and optical rotation. On the basis of DSC results a linear relation was found between the irradiation dose and the decrease in the melting point and increase in the enthalpy of melting, characterised by high correlation coefficients of r = 0.9839 and 0.9622, respectively. Moreover, a linear relation was established between the optical rotation angle and the irradiation dose, αD (°) = f(dose), characterised by the correlation coefficient r = 0.9874. The results obtained indicate that thiamphenicol can be safely subjected to radiation sterilization by the standard dose of 25 kGy. © 2007 Elsevier B.V. All rights reserved.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Szymańska2008447,

title = {The SAXS and rheological studies of HEWL amyloid formation},

author = {A. Szymańska and T. Hornowski and M. Kozak and G. Ślósarek},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-49149095302&doi=10.12693%2fAPhysPolA.114.447&partnerID=40&md5=74f3abc341b3351bfd33435f1b93533a},

doi = {10.12693/APhysPolA.114.447},

issn = {05874246},

year  = {2008},

date = {2008-01-01},

journal = {Acta Physica Polonica A},

volume = {114},

number = {2},

pages = {447 – 454},

publisher = {Polish Academy of Sciences},

abstract = {We performed small angle X-ray scattering and rheological experiments in order to analyze the aggregation and denaturation processes of hen egg white lysozyme initiated by the presence of ethanol molecule. At low ethanol concentrations (below 60% (v/v)) we did not observe any change of the radius of gyration of lysozyme and no drastic changes in viscosity of the protein solution. With the increase in ethanol concentration up to the final concentration of 85% (v/v) the viscosity of protein solution dramatically increased. For high ethanol concentration a pseudoplastic behavior of lysozyme solution was observed, indicating a process of aggregation and reorientation of the protein molecules. Similar effects were observed in small angle X-ray scattering experiments. We assume that the analysis of the aggregation processes of the hen egg white lysozyme could contribute to our understanding of the mechanism of lysozyme amyloid formation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Derylo-Marczewska20082851,

title = {Effect of addition of pore expanding agent on changes of structure characteristics of ordered mesoporous silicas},

author = {A. Derylo-Marczewska and A. W. Marczewski and I. Skrzypek and S. Pikus and M. Kozak},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-56949095874&doi=10.1016%2fj.apsusc.2008.08.026&partnerID=40&md5=5ba7b153644ebb13b60ce3feca86b313},

doi = {10.1016/j.apsusc.2008.08.026},

issn = {01694332},

year  = {2008},

date = {2008-01-01},

journal = {Applied Surface Science},

volume = {255},

number = {5 PART 2},

pages = {2851 – 2858},

publisher = {Elsevier},

abstract = {A series of mesoporous silica materials were synthesized by applying two types of Pluronic copolymers as pore creating agents. Differentiation of pore structure of the obtained sorbents was attained by changing the amount of trimethylbenzene as pore expander introduced to a reacting mixture. The parameters characterizing porous structure were estimated from nitrogen adsorption/desorption isotherms. The changes of pore arrangement in the synthesized materials were investigated by using X-ray diffraction. The structural transformations were found at the TMB/polymer ratio of 0.8 and 1. Correlations between the values of structure parameters and the content of TMB were found. © 2008.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Marciniec2007337,

title = {Thermal study of four irradiated imidazoline derivatives in solid state},

author = {Barbara Marciniec and M. Kozak and M. Naskrent and K. Dettlaff and M. Ogrodowczyk and M. Stawny and L. Wachowski},

url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-34248574466&doi=10.1007%2fs10973-006-8060-x&partnerID=40&md5=1787ba0c434553b2cbd7323749b00fbb},

doi = {10.1007/s10973-006-8060-x},

issn = {13886150},

year  = {2007},

date = {2007-01-01},

journal = {Journal of Thermal Analysis and Calorimetry},

volume = {88},

number = {2},

pages = {337 – 342},

abstract = {Four imidazoline derivatives: antazoline (AN), naphazoline (NN), tymazoline (TM), xylometazoline (XM), in the form of hydrochlorides in solid phase have been subjected to high energy e-beam irradiation from an accelerator (~10 MeV) at a dose varied from 25 to 200 kGy. The effects of the irradiation have been assessed by DSC, X-ray diffraction, FTIR, EPR and TLC. The standard sterilisation dose of 25 kGy has been found to produce changes in the properties of one derivative (XM), two other ones (AN and TM) have been found sensitive to doses >100 kGy, whereas NN has been resistant to irradiation in the whole range studied (25-200 kGy). EPR results indicated that the changes taking place in the therapeutic substances studied are related to radical formation. The irradiation induced changes in colour, a decrease or increase in the melting point, changes in the XRD pattern, small changes in the shape of FTIR peaks and the presence of radiolysis products. The XM compounds cannot be sterilised by irradiation because of the radiation induced changes in its physico-chemical properties. © Springer-Verlag 2007.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}